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Cardiorespiratory Events Associated With Ophthalmic Surgery

26 Feb 2020 1:45 PM | Anonymous

A Single-Center, Retrospective Records Review of 130,775 Patients, 1999-2015

Vinodkumar Singh, MD1,Ayesha S. Bryant, MSPH, MD1, Matthew Hull, MD1, Jason Skelley, MD1, Robin Walters, MD2 , R. Clark Cross, MD1, Marc A. Rozner, MD3 , and Gwendolyn L. Boyd, MD1

Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
2 Department of Anesthesiology, University of Kansas Medical Center, Kansas City, MO, USA
3 Baylor College of Medicine Education at The University of Texas MD Anderson Cancer Center, Houston, TX, USA 


Purpose: The most recent study of ophthalmic surgery morbidity and mortality was published in 1995, with a patient study population from 1977 to 1988. The present study reports surgical outcomes from a single-center, retrospective analysis of patient records from 1999 to 2015. Methods: Three International Classification of Diseases–9-CM codes for cardiorespiratory events were searched in the discharge diagnoses in an eye hospital over a 16-year period. The overall mortality and preoperative risk factors were analyzed, including the type of anesthetic, type of surgery, medical comorbidities, and bradycardia preceding the cardiac events. Results: Between February 1, 1999 and October 1, 2015, a total of 130 775 patients presented for ophthalmic surgery. Fifty-nine patients (0.45 per 1000) experienced a cardiorespiratory event. Of the 59 patients, 14 patients had a cardiorespiratory arrest, 9 of whom died during the perioperative period. Of the remaining 45 patients, 29 had significant adverse events needing some form of advanced monitoring, evaluation, and/or intervention. There was a significantly greater prevalence of diabetes among patients who had a cardiorespiratory event (P < .001). Conclusions: The major risk factor associated with ophthalmic surgery morbidity and mortality was diabetes with its associated complications of autonomic neuropathy, nephropathy, and retinopathy. Of the 9 patients who died, 8 were diabetic with proliferative diabetic retinopathy and renal  insufficiency/failure. The ninth mortality was secondary to a venous air embolism during ocular air infusion. The adage that “the eye is the window to our overall health” seems to be correct.

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